neurofibromatosis

American  

[noor-oh-fahy-broh-muh-toh-sis, nyoor-] / ˌnʊər oʊ faɪˌbroʊ məˈtoʊ sɪs, ˌnyʊər- /

noun

Pathology.

1. a dominantly inherited genetic disorder characterized by flat brown patches on the skin, neurofibromas of the skin and internal organs, and in some cases skeletal deformity.

---

neurofibromatosis British  

/ ˌnjʊərəʊˌfaɪbrəməˈtəʊsɪs /

noun

1. a condition characterized by the formation of benign tumours on the fibrous coverings of the peripheral nerves and the development of areas of café-au-lait spots

---

neurofibromatosis Scientific  

/ nr′ō-fī′brō-mə-tō′sĭs /

1. A genetic disease characterized by multiple benign tumors of peripheral nerves, called neurofibromas, and pigmented spots on the skin, sometimes accompanied by bone deformity and a predisposition to cancers, especially of the brain.

---

Etymology

Origin of neurofibromatosis

1895–1900; < New Latin neurofibromat-, stem of neurofibroma neurofibroma + -osis

Example Sentences

It could have so easily looked like a big stiff mask, but instead, the makeup truly made Sebastian look like a man with neurofibromatosis.

From Los Angeles Times

Maybe Stan, who won a Golden Globe for playing a struggling actor with neurofibromatosis in the dark satire “A Different Man.”

From Los Angeles Times

“I wanted to talk to Adam about how he was feeling about myself playing this part and having someone step into these shoes without neurofibromatosis,” he says.

From Los Angeles Times

The top prize was won by A Different Man, a superb and original film about an aspiring actor who has neurofibromatosis, a disfiguring facial condition.

From BBC

Growing up in England with neurofibromatosis type 1, a rare genetic disorder that causes tumors to grow on his face, Pearson was often taunted by classmates who cruelly called him “Elephant Man” and other names.

From Los Angeles Times