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nocebo

American  
[noh-see-boh] / noʊˈsi boʊ /

noun

  1. an inactive substance or a real medication that produces unpleasant or worsening symptoms in a patient or research participant because the person expects negative effects.

  2. a negative symptom experienced by a person with such expectations.


Etymology

Origin of nocebo

1960–65; Latin nocēbō “I shall be harmful”; patterned after placebo

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Conversely, those who received the placebo may have experienced a nocebo effect, which means worsening symptoms because they were aware they did not get active treatment.

From Salon • Aug. 6, 2024

The nocebo effect is often considered the mirror image of the placebo effect.

From Science Daily • Jun. 6, 2024

Both the placebo and nocebo effects influenced activity in the brainstem, the researchers report this week in The Journal of Neuroscience.

From Science Magazine • Oct. 26, 2021

“A nocebo effect could explain what is going on in this incident,” Dr. Ryan Marino, medical director of toxicology at University Hospitals in Cleveland, told the newspaper earlier this week.

From Seattle Times • Aug. 13, 2021

Research into the nocebo effect has been hampered by the ethics of subjecting people to it, but a picture of the mechanisms is emerging.

From Slate • Feb. 1, 2018

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