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nucleoid

American  
[noo-klee-oid, nyoo-] / ˈnu kliˌɔɪd, ˈnju- /

noun

  1. the central region in a prokaryotic cell, as a bacterium, that contains the chromosomes and that has no surrounding membrane.


adjective

  1. resembling a nucleus.

Usage

What is a nucleoid? A nucleoid is the central part of a prokaryotic cell that contains genetic material. A nucleoid is found only in a prokaryotic cell, such as a single-celled bacteria. It’s integral to reproduction and genetic behavior, housing chromosomes and DNA and, in some prokaryotic cells, additional DNA called plasmids. RNA and proteins can also be found within the nucleoid area. Nucleoid can be used to describe something that resembles a nucleus (a specialized mass of protoplasm encased in a double membrane). Example: If you examine the nucleoid of the bacteria, you’ll see that it lacks a specific chromosome related to that gene in similar organisms.

Etymology

Origin of nucleoid

First recorded in 1850–55; nucle(us) + -oid

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Most of these bead-like sections contain a nucleoid near the center, although the structures can also form without mtDNA present.

From Science Daily Apr. 13, 2026

They have a single piece of circular DNA in the nucleoid area of the cell.

From Textbooks Jun. 9, 2022

It has a cell wall enclosing nuclear membrane, cytoplasm, mitochondria, vacuoles and nucleoid region with genetic material.

From Textbooks Jun. 9, 2022

They typically have cell walls enclosing nuclear membranes, cytoplasm, ribosomes, mitochondria and nucleoid region with genetic material.

From Textbooks Jun. 9, 2022

It has a cell wall enclosing nuclear membrane, cytoplasm, ribosomes and nucleoid region with genetic material.

From Textbooks Jun. 9, 2022

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