Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
The 26-year-old, who underwent a heart transplant in 2012, began taking an off-label prescription for everolimus, a generic version of Novartis’s anti-rejection drug Zortress, a year later.
From MarketWatch ● Aug. 13, 2026
Given that MOTS-c is already widely used off-label and no research has shown evidence of harmful side effects, Cohen said in his remarks that he believed “quality-controlled, prescriber-supervised” compounding was the safest way forward.
From Los Angeles Times ● Aug. 6, 2026
But doctors prescribing the drugs off-label say the risks of obesity complications for some patients are too serious not to try a treatment that can be so effective.
From The Wall Street Journal ● Jun. 22, 2026
In May, Canada became the first country in the G7 to approve a generic semaglutide injection, intended for type 2 diabetes patients but can be prescribed off-label for weight loss.
From BBC ● Jun. 3, 2026
Researchers at the University of Connecticut report that the treatment caused significant brain damage in mice, raising concerns about its growing use in longevity research and off-label anti-aging therapies.
From Science Daily ● May 27, 2026
The Food and Drug Administration hasn’t approved atropine for this use, but ophthalmologists sometimes prescribe a very low dose off label.
From The Wall Street Journal ● Dec. 28, 2025
TikTok has helped fuel a trend of doctors prescribing the drug off label to people for weight loss, leading to a medication shortage for diabetic patients.
From Los Angeles Times ● Jan. 25, 2023
Since sodium phenylbutyrate is approved for another purpose, doctors are allowed to prescribe it off label for ALS.
From Washington Post ● Sep. 7, 2022
Doctors can prescribe it off label — as they already do when prescribing it as part of a mifepristone-misoprostol combo or when using it to induce labor.
From The Verge ● May 5, 2022
“I have never seen a case before this where the judge was asked to force someone to engage in an off label use,” he said.
From Seattle Times ● Oct. 16, 2021
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
