on-off phenomenon

[ ŏnôf ]

n.

A state in the treatment of Parkinson's disease with dopa in which the individual exhibits a rapid fluctuation of akinetic and choreoathetotic movements.

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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.