osteogenesis imperfecta

American  

[im-per-fek-tuh] / ˌɪm pərˈfɛk tə /

noun

Pathology.

1. a rare hereditary disease in which abnormal connective tissue development leads to fragile bones subject to fracture.

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osteogenesis imperfecta British  

/ ˌɪmpəˈfɛktə /

noun

1. Also called: brittle bone syndrome.  a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformities

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osteogenesis imperfecta Scientific  

/ ŏs′tē-ə-jĕn′ĭ-sĭsĭm′pər-fĕk′tə /

1. A hereditary disease characterized by abnormally brittle, easily fractured bones.

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Etymology

Origin of osteogenesis imperfecta

1900–05; < New Latin: imperfect osteogenesis

Example Sentences

However, Conservative peer Lord Shinkwin, who has rare brittle bone disease osteogenesis imperfecta, argued that peers had already "been generous with our time".

From BBC

The two biotechs are partners, as they are collaborating in the development of setrusumab for the treatment of osteogenesis imperfecta — a rare genetic bone metabolism disorder known as brittle-bone disease.

From MarketWatch

The companies said two Phase 3 trials for setrusumab to treat osteogenesis imperfecta, a rare bone disorder, didn’t meet their main goal of reducing fracture rates.

From Barron's

The companies said two Phase 3 trials for setrusumab to treat osteogenesis imperfecta, a rare bone disorder, didn’t meet their main goal of reducing fracture rates.

From Barron's

Kat has osteogenesis imperfecta type 3, known as brittle bone disease, and says she faces higher energy bills as she needs to charge her wheelchair and other equipment.

From BBC