a rare hereditary disease in which abnormal connective tissue development leads to fragile bones subject to fracture.
Origin of osteogenesis imperfecta
1900–05; < New Latin: imperfect osteogenesis
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019
a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformitiesAlso called: brittle bone syndrome
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
A hereditary disease marked by abnormal fragility and plasticity of bone, with deformity of long bones, a bluish discoloration of the sclerae, recurring fractures resulting from minimal trauma, and often otosclerosis.brittle bones
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
A hereditary disease characterized by abnormally brittle, easily fractured bones.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.