osteogenesis imperfecta


noun Pathology.

a rare hereditary disease in which abnormal connective tissue development leads to fragile bones subject to fracture.

Nearby words

  1. osteoectasia,
  2. osteofibroma,
  3. osteofibrosis,
  4. osteogen,
  5. osteogenesis,
  6. osteogenetic fiber,
  7. osteogenetic layer,
  8. osteogenic,
  9. osteogenic sarcoma,
  10. osteogenous

Origin of osteogenesis imperfecta

1900–05; < New Latin: imperfect osteogenesis

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for osteogenesis imperfecta

osteogenesis imperfecta


a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformitiesAlso called: brittle bone syndrome
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for osteogenesis imperfecta

osteogenesis imperfecta



A hereditary disease marked by abnormal fragility and plasticity of bone, with deformity of long bones, a bluish discoloration of the sclerae, recurring fractures resulting from minimal trauma, and often otosclerosis.brittle bones

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Science definitions for osteogenesis imperfecta

osteogenesis imperfecta

[ŏs′tē-ə-jĕnĭ-sĭs ĭm′pər-fĕktə]

A hereditary disease characterized by abnormally brittle, easily fractured bones.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.