osteogenesis imperfecta

[ im-per-fek-tuh ]

noun

, Pathology.

1. a rare hereditary disease in which abnormal connective tissue development leads to fragile bones subject to fracture.

osteogenesis imperfecta

/ ˌɪmpəˈfɛktə /

noun

1. a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformities Also calledbrittle bone syndrome

osteogenesis imperfecta

/ ŏs′tē-ə-jĕn′ĭ-sĭsĭm′pər-fĕk′tə /

1. A hereditary disease characterized by abnormally brittle, easily fractured bones.

Word History and Origins

Origin of osteogenesis imperfecta¹

1900–05; < New Latin: imperfect osteogenesis