osteogenesis imperfecta

[im-per-fek-tuh]

noun

Pathology.

1. a rare hereditary disease in which abnormal connective tissue development leads to fragile bones subject to fracture.

osteogenesis imperfecta

/ ˌɪmpəˈfɛktə /

noun

1. Also called: brittle bone syndrome. a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformities

osteogenesis imperfecta

1. A hereditary disease characterized by abnormally brittle, easily fractured bones.

Word History and Origins

Origin of osteogenesis imperfecta¹

1900–05; < New Latin: imperfect osteogenesis

Example Sentences

Em was born with osteogenesis imperfecta, also known as brittle bone disease, so her family has treated her delicately her entire life.

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I have lived with osteogenesis imperfecta my entire life and am a full-time wheelchair user.

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Chloe Morgan, 30, from Penllergaer near Swansea, has osteogenesis imperfecta, or brittle bone disease, which means she uses a wheelchair or an adapted car to leave the house.

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Due to her condition, osteogenesis imperfecta - which creates brittle bones - Ms Watkins said gaining proper healthcare is almost impossible.

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And will understanding this mechanism offer insights into conditions where something is wrong with collagen, such as osteogenesis imperfecta?

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