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ototoxic

American  
[oh-tuh-tok-sik] / ˌoʊ təˈtɒk sɪk /

adjective

  1. having a harmful effect on the organs or nerves concerned with hearing and balance.


Other Word Forms

  • ototoxicity noun

Etymology

Origin of ototoxic

First recorded in 1950–55; oto- + toxic

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Barr-Gillespie suggests a deeper knowledge of the transduction process might also prove helpful with hearing loss acquired from exposure to noise or ototoxic drugs—about half of the 460 million cases worldwide.

From Scientific American

In all, there are more than 200 known ototoxic medications on the market today, according to the American-Speech-Language-Hearing Association, which can also impact the ear's balance functions.​

From US News

Oricula Therapeutics – Developing medications to protect hearing and balance from the effects of aging and ototoxic drugs, or medications that are toxic to the ear.

From Seattle Times

Disruption of the sensory hair bundle by genetic mutation, loud sounds, or ototoxic drugs can lead to hair-cell dysfunction and deafness. 

From Science Magazine

The resulting expression stimulated regeneration of spiral ganglion neurites, which had atrophied 2 weeks after ototoxic treatment, in a bilateral sensorineural deafness model.

From Science Magazine