ototoxic

[oh-tuh-tok-sik]

adjective

1. having a harmful effect on the organs or nerves concerned with hearing and balance.

Other Word Forms

• ototoxicity noun

Word History and Origins

Origin of ototoxic¹

First recorded in 1950–55; oto- + toxic

Example Sentences

Barr-Gillespie suggests a deeper knowledge of the transduction process might also prove helpful with hearing loss acquired from exposure to noise or ototoxic drugs—about half of the 460 million cases worldwide.

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In all, there are more than 200 known ototoxic medications on the market today, according to the American-Speech-Language-Hearing Association, which can also impact the ear's balance functions.​

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Oricula Therapeutics – Developing medications to protect hearing and balance from the effects of aging and ototoxic drugs, or medications that are toxic to the ear.

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Disruption of the sensory hair bundle by genetic mutation, loud sounds, or ototoxic drugs can lead to hair-cell dysfunction and deafness. 

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The resulting expression stimulated regeneration of spiral ganglion neurites, which had atrophied 2 weeks after ototoxic treatment, in a bilateral sensorineural deafness model.

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