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oxidative stress

American  
[ahk-si-dayt-iv stres] / ˈɑk sɪˌdeɪt ɪv ˈstrɛs /

noun

  1. Physiology. an age-related condition of the body in which the production of oxidants and the increase in free radicals exceeds the ability of antioxidants to neutralize them, resulting in damage to cells, proteins, and DNA.


oxidative stress Scientific  
/ ŏk′sĭ-dātĭv /
  1. A condition of increased oxidant production in animal cells characterized by the release of free radicals and resulting in cellular degeneration.


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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The research team is continuing to investigate how food additives and ultra-processed foods influence inflammation, oxidative stress, blood metabolic markers, and the composition of the gut microbiota.

From Science Daily • Jun. 18, 2026

In contrast, stronger antioxidant activity was associated with lower oxidative stress and better fruit preservation.

From Science Daily • May 23, 2026

The team also measured levels of malondialdehyde, a marker of oxidative stress, after exposing skin to low doses of UV radiation.

From Science Daily • May 18, 2026

Participants who consumed grapes showed lower levels of this marker, suggesting reduced oxidative stress in the skin.

From Science Daily • May 18, 2026

“Do you understand the long-term issues of a cross-country run like you’re planning? Muscle damage, oxidative stress, enlargement of the heart, knee damage, hip and pelvis misalignment, should I go on?”

From "A Heart in a Body in the World" by Deb Caletti

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