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oxidative stress

American  
[ahk-si-dayt-iv stres] / ˈɑk sɪˌdeɪt ɪv ˈstrɛs /

noun

  1. Physiology. an age-related condition of the body in which the production of oxidants and the increase in free radicals exceeds the ability of antioxidants to neutralize them, resulting in damage to cells, proteins, and DNA.


oxidative stress Scientific  
/ ŏk′sĭ-dātĭv /
  1. A condition of increased oxidant production in animal cells characterized by the release of free radicals and resulting in cellular degeneration.


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Example Sentences

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Persistent oxidative stress can injure proteins, fats, and DNA and has been associated with aging and many chronic diseases.

From Science Daily Jul. 18, 2026

Cell-culture and mouse studies also suggest links to cancer, inflammation and oxidative stress.

From The Wall Street Journal Jul. 17, 2026

Overall, the study showed that PCAIs can produce powerful anticancer effects in pancreatic cancer cells by disrupting critical signaling networks, increasing oxidative stress, and activating apoptosis.

From Science Daily Jun. 29, 2026

"We are giving neurons their spark back by reducing oxidative stress and reactivating the brain's mitochondria," Narayana said.

From Science Daily May 26, 2026

“Do you understand the long-term issues of a cross-country run like you’re planning? Muscle damage, oxidative stress, enlargement of the heart, knee damage, hip and pelvis misalignment, should I go on?”

From "A Heart in a Body in the World" by Deb Caletti

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