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paroxetine

American  
[puh-rok-si-teen, par-ok-] / pəˈrɒk sɪˌtin, pærˈɒk- /

noun

Pharmacology.
  1. a drug, C 19 H 20 FNO 3 HCl, of the SSRI class, that acts by prolonging the action of serotonin in the brain, used in the treatment of depression and anxiety disorders.


paroxetine British  
/ pæˈrɒksətiːn /

noun

  1. an antidepressant drug that acts by preventing the re-uptake after release of serotonin in the brain, thereby prolonging its action: used for treating depression, obsessive-compulsive disorders, and panic disorder. Formula: C 19 H 20 FNO 3

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of paroxetine

First recorded in 1975–80; of uncertain origin, but perhaps based on piperidine ( def. ) with the infix ox- ( def. )

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Overall, the most prescribed class of antidepressants - SSRIs such as paroxetine, citalopram, escitalopram and sertraline - tended to have fewer physical side effects.

From BBC

Dr Toby Pillinger says: For Jane, some antidepressants are linked to higher cholesterol, including venlafaxine, duloxetine and paroxetine, so she might steer clear of those.

From BBC

Dr Toby Pillinger says: John should avoid drugs such as venlafaxine, amitriptyline or nortriptyline which raise blood pressure, and would be better suited to citalopram, escitalopram and paroxetine.

From BBC

These kinds of symptoms were more common after discontinuing treatment with the drugs imipramine, paroxetine, venlafaxine, and desvenlafaxine.

From Science Daily

The antidepressants sertraline and paroxetine, both greenlit by FDA in 2000, generally have a small effect and work in less than two-thirds of patients, Rothbaum notes.

From Science Magazine