pentose phosphate pathway

noun

1. a sequence of metabolic reactions by which NADPH is synthesized, together with ribose phosphate, part of the synthesis of nucleic acids

Example Sentences

Using mathematical modelling of cellular metabolism, the authors found that decreases in the production of lysine would result in an attenuated flux of molecules through the oxidative part of the pentose phosphate pathway — the metabolic pathway that is the dominant source of NADPH.

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Glucose therefore enters another metabolic pathway, the pentose phosphate pathway, which generates NADPH, a cofactor used by antioxidants.

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Patra, K. C. & Hay, N. The pentose phosphate pathway and cancer.

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Functionally, PFKFB4-driven SRC-3 activation drives glucose flux towards the pentose phosphate pathway and enables purine synthesis by transcriptionally upregulating the expression of the enzyme transketolase.

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