peptide bond

American  

noun

Biochemistry.

1. a covalent bond formed by joining the carboxyl group of one amino acid to the amino group of another, with the removal of a molecule of water.

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peptide bond British  

noun

1. biochem a chemical amide linkage, –NH–CO–, formed by the condensation of the amino group of one amino acid with the carboxyl group of another

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peptide bond Scientific  

1. The chemical bond formed between amino acids, constituting the primary linkage in all protein structures. In a peptide bond, the carboxyl group (COOH) of one amino acid bonds with the amino group (NH ₂) of another, forming the sequence CONH and releasing water (H ₂ O).

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Etymology

Origin of peptide bond

First recorded in 1930–35

Example Sentences

The formation of each peptide bond is catalyzed by peptidyl transferase, an RNA-based enzyme that is integrated into the 50S ribosomal subunit.

From Textbooks • Jun. 9, 2022

Each amino acid is linked to its neighbors by a peptide bond.

From Textbooks • Jun. 9, 2022

In the formation of this peptide bond, the amine replaces the OH to form O = C – NH2.

From Textbooks • Jun. 9, 2022

The peptide bond is formed between the amino group of one amino acid and the carboxyl group of another amino acid.

From Textbooks • Jan. 1, 2018

Pauling had cracked the a-helix by ruthlessly following up his knowledge that the peptide bond was flat.

From "Double Helix" by James D. Watson