pill

¹ American  

[pil] / pɪl /

noun

1. a small globular or rounded mass of medicinal substance, usually covered with a hard coating, that is to be swallowed whole.

2. something unpleasant that has to be accepted or endured.

   Ingratitude is a bitter pill.

3. Slang. a tiresomely disagreeable person.

4. Sports Slang. a ball, especially a baseball or golf ball.

5. the pill. birth-control pill.

6. British Slang. pills, billiards.

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verb (used with object)

1. to dose with pills.

2. to form or make into pills.

3. Slang. to blackball.

verb (used without object)

1. to form into small, pill-like balls, as the fuzz on a wool sweater.

idioms

1. Take a chill pill! chill pill.

pill ² American  

[pil] / pɪl /

verb (used with or without object)

1. British Dialect. to peel.

2. Obsolete. to become or cause to become bald.

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pill ³ American  

[pil] / pɪl /

verb (used with object)

Archaic.

1. to rob, plunder, or pillage.

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pill ¹ British  

/ pɪl /

noun

1. a small spherical or ovoid mass of a medicinal substance, intended to be swallowed whole

2. informal (sometimes capital) an oral contraceptive

3. something unpleasant that must be endured (esp in the phrase bitter pill to swallow )

4. slang a ball or disc

5. a small ball of matted fibres that forms on the surface of a fabric through rubbing

6. slang an unpleasant or boring person

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verb

1. (tr) to give pills to

2. (tr) to make pills of

3. (intr)

   1. to form into small balls

   2. (of a fabric) to form small balls of fibre on its surface through rubbing

4. slang (tr) to blackball

pill ² British  

/ pɪl /

verb

1. archaic to peel or skin (something)

2. archaic to pillage or plunder (a place)

3. obsolete to make or become bald

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pill More Idioms  

1. see bitter pill to swallow; sugar the pill.

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Etymology

Origin of pill¹

First recorded in 1375–1425; Middle English pille, from Middle Low German, Middle Dutch pille, Old French pile, from Latin pilula “little ball, globule, pellet,” diminutive of pila “ball”; see -ule

Origin of pill²

First recorded before 1100; Middle English pilen “to rob, steal, plunder,” Old English pilian “to skin, peel,” from Latin pilāre “to pluck, remove (hair or feathers)” see pile ³

Origin of pill³

First recorded in 1150–1200; Middle English pile(n), pille(n), pilie(n), probably conflation of pill ² with Middle French piller, peler ( see pillage)

Explanation

A small, round dose of medicine is a pill. If you get sick, you might take a pill, which is a pain because it usually tastes bad. A person who’s a pain can also be called a pill. In addition to medicine, you can take vitamins or other supplements in the form of a pill. Most pills have to be swallowed whole with water, but some can be chewed. Because of the association of pill with yucky medicine, there's also the colloquial meaning of "unpleasant person," like a little brother who's a total pill. And from the same association comes "a bitter pill to swallow," for "a difficult or painful necessity."

Example Sentences

Erasca, a biotech whose surging stock has given it a $6 billion market cap, is developing an earlier-stage RAS-targeting pill that some analysts believe could eventually rival daraxonrasib.

From The Wall Street Journal • Apr. 28, 2026

RevMed’s pill, daraxonrasib, targets a protein called RAS that, when mutated, fuels the majority of pancreatic tumors.

From The Wall Street Journal • Apr. 28, 2026

Veradermics is working on an extended-release version of oral minoxidil that is thought to reduce the heart palpitations and low blood pressure that can occur when people take higher doses of a minoxidil pill.

From MarketWatch • Apr. 27, 2026

Still, it’s difficult “not to be impressed” by Novo, which benefits from brand continuity as Lilly markets its pill under a completely new name.

From Barron's • Apr. 27, 2026

I don’t know how a pill can help me feel better.

From "Finding Junie Kim" by Ellen Oh

Related Words

• dose
• medicine
• tablet