[ pol-ee-noo-klee-uh-tahyd, -nyoo- ]
/ ˌpɒl iˈnu kli əˌtaɪd, -ˈnyu- /

noun Biochemistry.

a sequence of nucleotides, as in DNA or RNA, bound into a chain.

Origin of polynucleotide

First recorded in 1910–15; poly- + nucleotide
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for polynucleotide

/ (ˌpɒlɪˈnjuːklɪəˌtaɪd) /


biochem a molecular chain of nucleotides chemically bonded by a series of ester linkages between the phosphoryl group of one nucleotide and the hydroxyl group of the sugar in the adjacent nucleotide. Nucleic acids consist of long chains of polynucleotides
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medical definitions for polynucleotide

[ pŏl′ē-nōōklē-ə-tīd′ ]


A linear polymer containing an indefinite, usually large number of nucleotides linked from one ribose or deoxyribose to another by phosphoric residues.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.