• synonyms


[pol-ee-noo-klee-uh-tahyd, -nyoo-]
noun Biochemistry.
  1. a sequence of nucleotides, as in DNA or RNA, bound into a chain.
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Origin of polynucleotide

First recorded in 1910–15; poly- + nucleotide
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for polynucleotide


  1. biochem a molecular chain of nucleotides chemically bonded by a series of ester linkages between the phosphoryl group of one nucleotide and the hydroxyl group of the sugar in the adjacent nucleotide. Nucleic acids consist of long chains of polynucleotides
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Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

polynucleotide in Medicine


  1. A linear polymer containing an indefinite, usually large number of nucleotides linked from one ribose or deoxyribose to another by phosphoric residues.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.