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Synonyms

pox

American  
[poks] / pɒks /

noun

Pathology.
  1. a disease characterized by multiple skin pustules, as smallpox.

  2. syphilis.

  3. Also called soil rotPlant Pathology. a disease of sweet potatoes, characterized by numerous pitlike lesions on the roots, caused by a fungus, Streptomyces ipomoea.

  4. (used as an interjection to express distaste, rejection, aversion, etc.).

    A pox on you and your bright ideas!


pox British  
/ pɒks /

noun

  1. any disease characterized by the formation of pustules on the skin that often leave pockmarks when healed

  2. an informal name for syphilis

  3. archaic (interjection) an expression of intense disgust or aversion for someone

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of pox

1540–50 (earlier as surname); spelling variant of pocks, plural of pock

Explanation

A pox is an illness, especially one that's particularly contagious and causes blisters or rashes. Today, most poxes are preventable through vaccines. The most devastating of the poxes was probably smallpox, a viral disease that killed around 500 million people during the 20th century before being officially eradicated in 1980. A more common pox is chickenpox, which is highly infectious and can be fatal but is not as deadly. What these illnesses have in common is scarring blisters, once known themselves as pox, from pock, "pustule or blister."

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Vocabulary lists containing pox

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

A National Scientific Committee for the Management and Control of Sheep and Goat Pox was only established only in late October - a full 14 months after the first case was detected.

From BBC • Nov. 30, 2025

District Judge John McConnell issued a written decision in favor of an insurance company that had refused to pay an $85,000 claim to Carman for the loss of his 31-foot fishing boat, The Chicken Pox.

From Seattle Times • May 10, 2022

In September 2016, he arranged to go on a fishing trip with his mother on his boat named the Chicken Pox.

From Washington Post • May 10, 2022

Syphilis, known as the "Great Pox," was treated with mercury.

From Salon • Nov. 14, 2021

Examples of such diseases are:—Scarlet Fever, Diphtheria, Small Pox, Cholera, Yellow Fever, Tuberculous Disease, Ague, Hydrophobia, Cattle Plague, Anthrax; and many others might be enumerated whose dependence upon parasitic Germs is almost conclusively proved. 

From Addresses & Papers / Collectanea by Eade, Peter