- the first stage of syphilis, characterized by the formation of a chancre at the site of infection.
Origin of primary syphilis
First recorded in 1900–05
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- The first stage of syphilis, marked by formation of a painless chancre at the point of infection and by hardening and swelling of adjacent lymph nodes.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.