noun Biochemistry.

a macromolecule composed of a polysaccharide joined to a polypeptide and forming the ground substance of connective tissue.

Nearby words

  1. protend,
  2. protensive,
  3. protensively,
  4. proteo-,
  5. proteoclastic,
  6. proteolipid,
  7. proteolysis,
  8. proteolytic,
  9. proteome,
  10. proteometabolism

Origin of proteoglycan

1969; prote(in) + -o- + glyc- + -an, variant of -ane Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Medicine definitions for proteoglycan


[prō′tē-ō-glīkăn′, -kən]


Any of various mucopolysaccharides that are bound to protein chains in covalent complexes and occur in the extracellular matrix of connective tissue.

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.