proton pump inhibitor

[ proh-ton puhmp in-hib-i-ter ]
/ ˈproʊ tɒn ˌpʌmp ɪnˌhɪb ɪ tər /
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noun Pharmacology.

any of a group of drugs that reduce the production of gastric acid, thereby alleviating acid reflux; promoting the healing of ulcers in the stomach, duodenum, and esophagus; and preventing new ulcers from forming. Abbreviation: PPI



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Origin of proton pump inhibitor

First recorded in 1980–85
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2021

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British Dictionary definitions for proton pump inhibitor

proton-pump inhibitor


any of a group of drugs used to treat excessive secretion of acid in the stomach and any resulting ulcers. They block the enzyme (proton pump) in the cells of the gastric glands that secrete hydrochloric acid
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medical definitions for proton pump inhibitor

proton pump inhibitor


A class of drugs that inhibit gastric acid secretion by interfering with the movement of hydrogen ions across cell membranes and are used mainly to treat peptic ulcers, gastroesophageal reflux disease, and esophagitis.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.