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pyrazinamide

American  
[pir-uh-zin-uh-mahyd, -mid] / ˌpɪr əˈzɪn əˌmaɪd, -mɪd /

noun

Pharmacology.
  1. a substance, C 5 H 5 N 3 O, used in the treatment of tuberculosis.


Etymology

Origin of pyrazinamide

1950–55; pyrazine (< German Pyrazin, alteration of Pyridin pyridine, by insertion of az- az- ) + amide

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Early results from the TB Alliance trial on bedaquiline, clofazimine, PA-824 and pyrazinamide also look encouraging.

From Nature • Oct. 9, 2013

The new combination therapy consists of PA-824, a novel drug in the TB pipeline; moxifloxacin, an antibiotic for treating pneumonia and sinus infections; and pyrazinamide, a TB drug developed in 1952.

From Nature • Jul. 25, 2012

But pyrazinamide didn't make it through the three Ms: It does nothing in the dish—there's no MIC whatsoever—and it has a weak effect in mice.

From Slate • Nov. 16, 2011

Take the example of pyrazinamide, one of the front-line drugs in the treatment of tuberculosis.

From Slate • Nov. 16, 2011