[pahy-ruh-meth-uh-meen, -min]

noun Pharmacology.

a potent substance, C12H13ClN4, used against susceptible plasmodia in the prophylactic treatment of malaria and against Toxoplasma gondi in the treatment of toxoplasmosis.

Origin of pyrimethamine

First recorded in 1950–55; pyrim(idine) + eth(yl) + -amine Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

pyrimethamine in Medicine


[pī′rə-mĕthə-mēn′, -mĭn]


A potent folic acid antagonist used as a prophylactic antimalarial agent against Plasmodium falciparum and in the treatment of toxoplasmosis.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.