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refractory period

American  

noun

Physiology.
  1. a short period after a nerve or muscle cell fires during which the cell cannot respond to additional stimulation.


refractory period British  

noun

  1. a period during which a nerve or muscle is incapable of responding to stimulation, esp immediately following a previous stimulation. In an absolute refractory period there is a total inability to respond; in an effective or relative refractory period there is a response to very large stimuli

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

refractory period Scientific  
  1. The period immediately following the transmission of an impulse in nerve or muscle, in which a neuron or muscle cell regains its ability to transmit another impulse.

  2. See more at action potential


Etymology

Origin of refractory period

First recorded in 1875–80

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

During the refractory period, the membrane cannot generate another action potential.

From Textbooks • Jun. 9, 2022

The refractory period allows the voltage-sensitive ion channels to return to their resting configurations.

From Textbooks • Jun. 9, 2022

With a crew of dedicated sailors helping him reload, Greyjoy’s scorpion has a refractory period of less than a minute.

From Slate • May 7, 2019

Their influx through slow calcium channels accounts for the prolonged plateau phase and absolute refractory period that enable cardiac muscle to function properly.

From Textbooks • Jun. 19, 2013

There are two phases of the refractory period: the absolute refractory period and the relative refractory period.

From Textbooks • Jun. 19, 2013