- the aggregate of the phagocytic cells, including certain cells of the bone marrow, lymphatic system, liver, and spleen, that have reticular and endothelial characteristics and function in the immune system's defense against foreign bodies. Abbreviation: RES
Origin of reticuloendothelial system
First recorded in 1920–25
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- The diffuse system constituting all phagocytic cells of the body except granulocytes including the cells lining the sinusoids of the spleen, lymph nodes, and bone marrow along with the fibroblastic reticular cells of hematopoietic tissues.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.