scleroderma

[ skleer-uh-dur-muh, skler- ]

/ ˌsklɪər əˈdɜr mə, ˌsklɛr- /

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noun Pathology.

a disease in which connective tissue anywhere in the body becomes hardened and rigid.

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Origin of scleroderma

First recorded in 1865–70; sclero- + -derma

Words nearby scleroderma

sclerema, sclerenchyma, sclerite, scleritis, sclero-, scleroderma, sclerodermatous, scleroid, scleroma, sclerometer, sclerophyll

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use scleroderma in a sentence

She has pulmonary hypertension, fibromyalgia and the connective tissue disease scleroderma.
At a long COVID clinic, here’s how doctors are trying to help one woman who is struggling|Meghan Rosen|November 17, 2022|Science News
Is there any difficulty in reaching a diagnosis in scleroderma?
Essentials of Diseases of the Skin|Henry Weightman Stelwagon
In some instances such patches are seen in association with the more classic type of scleroderma just defined.
Essentials of Diseases of the Skin|Henry Weightman Stelwagon
The prognosis of the variety known as morphœa is less unfavorable than general scleroderma, and recovery more frequent.
Essentials of Diseases of the Skin|Henry Weightman Stelwagon

Allied to Scleroderma and distinguished by the cavities of the gleba containing distinct peridioles.
The Mushroom, Edible and Otherwise|M. E. Hard
The genus Geaster does not appear in the collection, nor Scleroderma.
Fungi: Their Nature and Uses|Mordecai Cubitt Cooke

British Dictionary definitions for scleroderma

scleroderma

sclerodermia (ˌsklɪərəʊˈdɜːmɪə) or scleriasis (sklɪˈraɪəsɪs)

/ (ˌsklɪərəʊˈdɜːmə) /

noun

a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin

Word Origin for scleroderma

C19: from New Latin sclerōdermus, from Greek, from sklēros hard + derma skin

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Scientific definitions for scleroderma

scleroderma

[ sklîr′ə-dûr′mə ]

A connective tissue disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.