• synonyms


[skleer-uh-dur-muh, skler-]
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noun Pathology.
  1. a disease in which connective tissue anywhere in the body becomes hardened and rigid.
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Origin of scleroderma

First recorded in 1865–70; sclero- + -derma
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

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Historical Examples

British Dictionary definitions for scleroderma


sclerodermia (ˌsklɪərəʊˈdɜːmɪə) or scleriasis (sklɪˈraɪəsɪs)

  1. a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin
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Word Origin

C19: from New Latin sclerōdermus, from Greek, from sklēros hard + derma skin
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for scleroderma


1866, from Modern Latin, from Greek skleros "hard" (see sclerosis) + derma "skin" (see derma). Related: Sclerodermatous; sclerodermatic.

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Online Etymology Dictionary, © 2010 Douglas Harper

scleroderma in Medicine


  1. A collagen disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.dermatosclerosis
  2. progressive systemic sclerosis
Related formsscle′ro•derma•tous (-mə-təs) adj.

scleroderma in Science