scleroderma

[ skleer-uh-dur-muh, skler- ]

noun

, Pathology.

1. a disease in which connective tissue anywhere in the body becomes hardened and rigid.

scleroderma

/ sklɪˈraɪəsɪs; ˌsklɪərəʊˈdɜːmɪə; ˌsklɪərəʊˈdɜːmə /

noun

1. a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin

scleroderma

/ sklîr′ə-dûr′mə /

1. A connective tissue disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.

Word History and Origins

Origin of scleroderma¹

First recorded in 1865–70; sclero- + -derma

Word History and Origins

Origin of scleroderma¹

C19: from New Latin sclerōdermus, from Greek, from sklēros hard + derma skin

Example Sentences

She has pulmonary hypertension, fibromyalgia and the connective tissue disease scleroderma.

From Science News

Is there any difficulty in reaching a diagnosis in scleroderma?

From Project Gutenberg

In some instances such patches are seen in association with the more classic type of scleroderma just defined.

From Project Gutenberg

The prognosis of the variety known as morphœa is less unfavorable than general scleroderma, and recovery more frequent.

From Project Gutenberg

Allied to Scleroderma and distinguished by the cavities of the gleba containing distinct peridioles.

From Project Gutenberg

The genus Geaster does not appear in the collection, nor Scleroderma.

From Project Gutenberg