[sem-ee-sin-thet-ik, sem-ahy-]

adjective Chemistry.

derived synthetically from one or more substances of natural origin.

Origin of semisynthetic

First recorded in 1935–40; semi- + synthetic Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

semisynthetic in Medicine


[sĕm′ē-sĭn-thĕtĭk, sĕm′ī-]


Prepared by chemical synthesis from natural materials, as of a pharmaceutical.
Consisting of a mixture of natural and synthetic substances.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.