sepsis

American  

[sep-sis] / ˈsɛp sɪs /

noun

Pathology.

1. local or generalized invasion of the body by pathogenic microorganisms or their toxins.

   dental sepsis; wound sepsis.

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sepsis British  

/ ˈsɛpsɪs /

noun

1. the presence of pus-forming bacteria in the body

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sepsis Scientific  

/ sĕp′sĭs /

1. A severe infection caused by pathogenic organisms, especially bacteria, in the blood or tissues. If untreated, a localized infection, as in the respiratory or urinary tracts, can lead to infection in the bloodstream and widespread inflammation, characterized initially by fever, chills, and other symptoms and later by septic shock.

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Etymology

Origin of sepsis

First recorded in 1855–60; from Greek sêpsis “decay”; compare sḗpein “to make rotten”

Example Sentences

It has further ongoing and planned trials for the treatment of bladder cancer, non-small-cell lung cancer, glioblastoma, sepsis, Non-Hodgkin lymphoma, and lymphopenia.

From Barron's • Mar. 24, 2026

Ellen thought he was showing signs of sepsis but "meningitis never once came into my head".

From BBC • Mar. 20, 2026

A pathologist also identified that sepsis was a factor in his death, "although evidence of any infection could not be found".

From BBC • Mar. 16, 2026

"We are now giving further training to staff on the prompt recognition of sepsis, and have taken measures to make sure antibiotic prescribing is done correctly."

From BBC • Mar. 11, 2026

The doctor told my mother that if I had remained in Africa another day or two, the infection would have spread through my body, causing sepsis.

From "Taking Flight: From War Orphan to Star Ballerina" by Michaela DePrince