serotonergic

[ser-uh-tn-ur-jik]

adjective

1. containing or activated by serotonin.

Word History and Origins

Origin of serotonergic¹

First recorded in 1965–70; seroton(in) + -ergic

Example Sentences

“Having an underlying biological rationale for a treatment — that is, the modulation of serotonergic function — also helped to improve the public understanding of the role of mental-health professionals,” they wrote, “as it provided a clear basis for discussing the biology of a psychiatric disorder.”

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“The serotonergic system is an absolute focus, it’s just other aspects of the neurotransmission in the serotonin system that is gaining traction.”

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The findings also have implications for disorders involving dopamine and serotonin dysfunction, such as addiction, where dopaminergic hypersensitivity and serotonergic deficits contribute to compulsive reward-seeking -- and in mood disorders including depression and anxiety, where diminished serotonin signaling might impair behavioral flexibility and long-term planning.

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“It is established that serotonergic psychedelics have immunomodulator and anti-inflammatory properties,” Kelly said.

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It points to fascinating directions for future research into the effects of serotonergic psychedelics on the gut.

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