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sickle cell

American  

noun

Pathology.
  1. an abnormal red blood cell having an elongated, crescentlike shape due to the presence of an abnormal hemoglobin.


Etymology

Origin of sickle cell

First recorded in 1925–30; so called from the fact that the cells are often sickle-shaped

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Without any products on the market, Fulcrum Therapeutics had been striving to commercialize its experimental drug for sickle cell disease, but those plans appear to now be on hold.

From Barron's • Jun. 2, 2026

The Cambridge, Mass.-based biopharmaceutical company said it has discontinued its pociredir program for the treatment of sickle cell disease and launched “a comprehensive review of strategic alternatives to maximize stockholder value.”

From Barron's • Jun. 2, 2026

A model of how one of GluBio’s experimental ‘molecular glue’ drugs causes two proteins in the human body, WIZ and cereblon, to stick to each other in a way designed to relieve sickle cell disease.

From The Wall Street Journal • Apr. 11, 2026

I see what happens in sickle cell warriors and people without sickle cell who just age without moving frequently.

From Los Angeles Times • Feb. 23, 2026

Unexplained vaginal bleeding and blood in urine during last two pregnancies; physician recommended sickle cell test.

From "The Immortal Life of Henrietta Lacks" by Rebecca Skloot

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