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Synonyms

side effect

American  
Or side-effect

noun

  • side effects
    plural
  1. any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

  2. any accompanying or consequential and usually detrimental effect.

    the side effects of air pollution.


side effect British  

noun

  1. any unwanted nontherapeutic effect caused by a drug Compare aftereffect

  2. any secondary effect, esp an undesirable one

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Noun Inflected Forms

Etymology

Origin of side effect

First recorded in 1880–85

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

That’s an inevitable side effect of appearing on a Bill Lawrence show.

From Los Angeles Times Aug. 10, 2026

A wave of artificial-intelligence adoption has come with an undesirable side effect: An explosion of cyberthreats.

From MarketWatch Aug. 2, 2026

Sam experienced one bout of excruciating pain a week after the procedure, a known but uncommon side effect of vasectomies according to Dr Salkeld, but that subsided after a few hours.

From BBC Aug. 1, 2026

Another potential side effect is an increase in the number of red blood cells.

From The Wall Street Journal Jul. 31, 2026

It wasn't the point of the paper chain, but it was a great side effect.

From "Linked" by Gordon Korman

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