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sister chromatid

[sis-ter kroh-muh-tid]

noun

  1. Biology.,  either of the twin chromatids, joined by a centromere, that are formed when a chromosome splits before cell division.



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Puget, N., Knowlton, M. & Scully, R. Molecular analysis of sister chromatid recombination in mammalian cells.

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Defects in chromosome segregation can arise directly through defects in the mitotic checkpoint, sister chromatid cohesion, spindle geometry and spindle dynamics.

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We thank A. McArthur and C. Guess for editing the manuscript, J. Temirov for help with sister chromatid analysis, J. Thurman for help with histology, F. Krafcik for help with cell culture, J. Wu and C. Billups for statistical analysis, J. Jeon for help with lentiviral preparations and C. Bradley for assistance with preclinical testing.

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