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Synonyms

softening of the brain

American  

noun

Pathology.
  1. a softening of the cerebrum, caused by impairment of the blood supply; encephalomalacia.

  2. Informal. dementia associated with general paresis.


softening of the brain British  

noun

  1. an abnormal softening of the tissues of the cerebrum characterized by various degrees of mental impairment

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of softening of the brain

First recorded in 1825–35

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The death rate is 89.4 per 100,000, substantially that of nephritis, 90.1, and cerebral hemorrhage and softening of the brain, 90.4; all diseases of middle and advanced age.

From Time Magazine Archive

He dutifully went under canvas with his pugnacious battalion, but he was pretty much of a failure, declined into rose pruning, and died after a sad "softening of the brain."

From Time Magazine Archive

All had softening of the brain, all were paralytic.

From Time Magazine Archive

The other, who returned to his old habits, died in two years from softening of the brain.

From The Intellectual Life by Hamerton, Philip Gilbert

He had softening of the brain, brought on by grief.

From The Spectacle Man A Story of the Missing Bridge by Leonard, Mary Finley