spectinomycin

[spek-tuh-noh-mahy-sin]

noun

Pharmacology.

1. an antibiotic drug, C 1 4 H 2 4 N 2 O 7 , produced by the actinomycete Streptomyces spectabilis, used in the treatment of susceptible gonorrhea.

Word History and Origins

Origin of spectinomycin¹

1960–65; blend of New Latin spectabilis a specific epithet (literally, visible; spectacle, -able ) and actinomycin

Example Sentences

To address this, the scientists designed new versions of the drug spectinomycin that overcome efflux, the main mechanism driving resistance.

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The new guidelines suggest trying combinations of drugs, including older antibiotics like gentamicin and spectinomycin.

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Researchers at St Jude Children's Research Hospital in Memphis, Tennessee, changed the chemical structure of an existing antibiotic, spectinomycin, to create a class of antibiotics called spectinamides that are effective against new targets.

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To create the spectinamides, the researchers designed complex three-dimensional models to examine how spectinomycin binds to the TB ribosome, where proteins are synthesized.

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