spermidine

American

[spur-mi-deen, -din] / ˈspɜr mɪˌdin, -dɪn /

noun

Biochemistry.

a biogenic polyamine, H 2 N(CH2 ) 4 NH(CH2 ) 3 NH 2 , formed from putrescine, occurring widely in nature and first identified in semen.

Etymology

Origin of spermidine

First recorded in 1925–30; sperm- + -idine

Example Sentences

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spermidine

A naturally occurring compound called spermidine may help strengthen vaccine responses in some older adults by reducing biological signs of immune system aging, according to research published in Aging Cell.

From Science Daily ● Jul. 21, 2026

"Larger studies will be needed to determine whether spermidine can consistently improve vaccine responses and whether similar effects are seen with other vaccines, such as those used against seasonal influenza."

From Science Daily ● Jul. 21, 2026

Lubiprostone increased the production of spermidine, a naturally occurring compound tied to healthier mitochondrial activity.

From Science Daily ● May 8, 2026

One possible way to explain this is if the core apoptotic machinery prevents ornithine from entering the mitochondrion and instead diverts it towards spermidine production.

From Nature ● Mar. 17, 2020

The apoptotic cells released spermidine, but not putrescine.

From Nature ● Mar. 17, 2020

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023