spermidine

American

[spur-mi-deen, -din] / ˈspɜr mɪˌdin, -dɪn /

noun

Biochemistry.

a biogenic polyamine, H 2 N(CH2 ) 4 NH(CH2 ) 3 NH 2 , formed from putrescine, occurring widely in nature and first identified in semen.

Etymology

Origin of spermidine

First recorded in 1925–30; sperm- + -idine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

spermidine

"Larger studies will be needed to determine whether spermidine can consistently improve vaccine responses and whether similar effects are seen with other vaccines, such as those used against seasonal influenza."

From Science Daily ● Jul. 21, 2026

After receiving their third COVID-19 vaccination, participants took either six milligrams of spermidine or a placebo each day for 13 weeks.

From Science Daily ● Jul. 21, 2026

They first reduced polyamine levels using a drug, then restored them by adding spermidine.

From Science Daily ● Mar. 2, 2026

One possible way to explain this is if the core apoptotic machinery prevents ornithine from entering the mitochondrion and instead diverts it towards spermidine production.

From Nature ● Mar. 17, 2020

It is possible that spermidine acts to increase such anti-inflammatory signalling from the adenosine receptors.

From Nature ● Mar. 17, 2020

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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023