spermidine

American  

[spur-mi-deen, -din] / ˈspɜr mɪˌdin, -dɪn /

noun

Biochemistry.

1. a biogenic polyamine, H 2 N(CH2 ) 4 NH(CH2 ) 3 NH 2 , formed from putrescine, occurring widely in nature and first identified in semen.

---

Etymology

Origin of spermidine

First recorded in 1925–30; sperm- + -idine

Example Sentences

See Examples For:

spermidine

Because the study included only 40 participants, the researchers caution that the results should be viewed as early evidence rather than definitive proof that spermidine can improve vaccination outcomes.

From Science Daily ● Jul. 21, 2026

Lubiprostone increased the production of spermidine, a naturally occurring compound tied to healthier mitochondrial activity.

From Science Daily ● May 8, 2026

They determined that lubiprostone boosts the production of spermidine, a compound that enhances mitochondrial activity by encouraging the growth of beneficial gut bacteria.

From Science Daily ● Dec. 3, 2025

Production of the molecules spermidine and putrescine becomes higher than normal.

From Nature ● Mar. 17, 2020

One possible way to explain this is if the core apoptotic machinery prevents ornithine from entering the mitochondrion and instead diverts it towards spermidine production.

From Nature ● Mar. 17, 2020