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spironolactone

American  
[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-] / ˌspaɪ rə noʊˈlæk toʊn, spaɪˌroʊ-, -ˌrɒn ə- /

noun

Pharmacology.
  1. a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.


spironolactone British  
/ ˌspaɪrənəʊˈlæktəʊn /

noun

  1. a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of spironolactone

1955–60; alteration of spirolactone; see spiro- 2, lactone

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Cooper asked USA Powerlifting for a “therapeutic-use exemption” to take spironolactone, a medicine prescribed to treat her gender dysphoria, “but JayCee was denied because she’s transgender,” Braverman said.

From Seattle Times Mar. 18, 2024

I also take several pills each morning to maintain the proper hormonal balance in my body: spironolactone to suppress testosterone and estradiol to increase estrogen.

From Salon Apr. 7, 2023

Cooper, who was taking the testosterone-reducing drug spironolactone, continued to compete in contests run by Open Powerlifting, capturing first place in five championship events in 2019.

From Washington Times Mar. 2, 2023

Other oral prescription medications have been used to treat hair loss over the past 10 to 20 years: spironolactone, finasteride and dutasteride.

From Washington Post Oct. 17, 2022

More recently, for women with hormone-related acne, long-term antibiotics have been replaced by spironolactone, a prescription oral blood pressure medication.

From New York Times Oct. 25, 2021

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