spironolactone

American  

[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-] / ˌspaɪ rə noʊˈlæk toʊn, spaɪˌroʊ-, -ˌrɒn ə- /

noun

Pharmacology.

1. a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.

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spironolactone British  

/ ˌspaɪrənəʊˈlæktəʊn /

noun

1. a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure

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Etymology

Origin of spironolactone

1955–60; alteration of spirolactone; see spiro- ², lactone

Example Sentences

Cooper asked USA Powerlifting for a “therapeutic-use exemption” to take spironolactone, a medicine prescribed to treat her gender dysphoria, “but JayCee was denied because she’s transgender,” Braverman said.

From Seattle Times • Mar. 18, 2024

Cooper, who was taking the testosterone-reducing drug spironolactone, continued to compete in contests run by Open Powerlifting, capturing first place in five championship events in 2019.

From Washington Times • Mar. 2, 2023

Food and Drug Administration to treat primary aldosteronism, spironolactone, was developed in the late 1950s.

From Salon • Feb. 26, 2022

She said the spironolactone treatment resulted in muscle loss and she has been unable to replicate her previous training and race times.

From Washington Post • Jan. 10, 2022

More recently, for women with hormone-related acne, long-term antibiotics have been replaced by spironolactone, a prescription oral blood pressure medication.

From New York Times • Oct. 25, 2021