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spironolactone

American  
[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-] / ˌspaɪ rə noʊˈlæk toʊn, spaɪˌroʊ-, -ˌrɒn ə- /

noun

Pharmacology.
  1. a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.


spironolactone British  
/ ˌspaɪrənəʊˈlæktəʊn /

noun

  1. a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of spironolactone

1955–60; alteration of spirolactone; spiro- 2, lactone

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

I also take several pills each morning to maintain the proper hormonal balance in my body: spironolactone to suppress testosterone and estradiol to increase estrogen.

From Salon

Other oral prescription medications have been used to treat hair loss over the past 10 to 20 years: spironolactone, finasteride and dutasteride.

From Washington Post

Food and Drug Administration to treat primary aldosteronism, spironolactone, was developed in the late 1950s.

From Salon

She said the spironolactone treatment resulted in muscle loss and she has been unable to replicate her previous training and race times.

From Washington Post

Dr. Engelman likes Prose, which makes supplements that are tailored to age, hair type, lifestyle and other factors, and the prescription drug spironolactone, which is an androgen blocker and can also help with acne.

From New York Times