spironolactone

[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-]

noun

Pharmacology.

1. a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.

spironolactone

/ ˌspaɪrənəʊˈlæktəʊn /

noun

1. a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure

Word History and Origins

Origin of spironolactone¹

1955–60; alteration of spirolactone; spiro- ², lactone

Word History and Origins

Origin of spironolactone¹

C20: from _spiro- ² + linking syllable -no- + _lactone

Example Sentences

I also take several pills each morning to maintain the proper hormonal balance in my body: spironolactone to suppress testosterone and estradiol to increase estrogen.

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A toxicology analysis turned up positive for the diuretic spironolactone — commonly known by its brand name, Aldactone — and metformin, a diabetes medication that bodybuilders use for weight loss.

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Other oral prescription medications have been used to treat hair loss over the past 10 to 20 years: spironolactone, finasteride and dutasteride.

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So some dermatologists, including Dr. Sinclair, have added another drug — very low doses of spironolactone, a blood pressure drug that also blocks certain sex hormones called androgens — to try to prevent unwanted hair growth.

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Food and Drug Administration to treat primary aldosteronism, spironolactone, was developed in the late 1950s.

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