spironolactone

American  

[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-] / ˌspaɪ rə noʊˈlæk toʊn, spaɪˌroʊ-, -ˌrɒn ə- /

noun

Pharmacology.

1. a steroid, C 2 4 H 3 2 O 4 S, used in combination with other drugs as a diuretic and antihypertensive.

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spironolactone British  

/ ˌspaɪrənəʊˈlæktəʊn /

noun

1. a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure

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Etymology

Origin of spironolactone

1955–60; alteration of spirolactone; see spiro- ², lactone

Example Sentences

Cooper asked USA Powerlifting for a “therapeutic-use exemption” to take spironolactone, a medicine prescribed to treat her gender dysphoria, “but JayCee was denied because she’s transgender,” Braverman said.

From Seattle Times • Mar. 18, 2024

I also take several pills each morning to maintain the proper hormonal balance in my body: spironolactone to suppress testosterone and estradiol to increase estrogen.

From Salon • Apr. 7, 2023

Cooper, who was taking the testosterone-reducing drug spironolactone, continued to compete in contests run by Open Powerlifting, capturing first place in five championship events in 2019.

From Washington Times • Mar. 2, 2023

Other oral prescription medications have been used to treat hair loss over the past 10 to 20 years: spironolactone, finasteride and dutasteride.

From Washington Post • Oct. 17, 2022

Dr. Engelman likes Prose, which makes supplements that are tailored to age, hair type, lifestyle and other factors, and the prescription drug spironolactone, which is an androgen blocker and can also help with acne.

From New York Times • Dec. 21, 2021