[spahy-ruh-noh-lak-tohn, spahy-roh-, -ron-uh-]

noun Pharmacology.

a steroid, C24H32O4S, used in combination with other drugs as a diuretic and antihypertensive.

Origin of spironolactone

1955–60; alteration of spirolactone; see spiro-2, lactone
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British Dictionary definitions for spironolactone



a diuretic that increases water loss from the kidneys and is much used to treat oedema in heart and kidney failure

Word Origin for spironolactone

C20: from spiro- ² + linking syllable -no- + lactone
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012