a combining form representing spleen in compound words: splenomegaly.
Also especially before a vowel, splen-.
Origin of spleno-
combining form representing Greek splḗn spleen
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.