spreading depolarization

American

[spred-ing dee-poh-luh-rahy-zey-shuhn] / ˈsprɛd ɪŋ diˌpoʊ lə raɪˈzeɪ ʃən /

noun

Pathology.

a wave of injury killing many neurons in the brain, spreading outward from the site of a stroke or other brain trauma as an increasing number of neurons release their glutamine.

Etymology

Origin of spreading depolarization

First recorded in 1990–95

Example Sentences

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spreading depolarization

The action potential travels down the axon as voltage-gated ion channels are opened by the spreading depolarization.

From Textbooks ● Jun. 19, 2013

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023