A remedy that won't fail, as in Hard work is a sure cure for brooding. Originating in the late 1800s as an advertising slogan (Dr. Keck's Sure Cure for Catarrh; first recorded in 1881), this rhyming phrase was soon extended to other matters.
The American Heritage® Idioms Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
How to use sure cure in a sentence
It was called rock oil and was hawked about the streets as a sure cure for rheumatism.
He advocated no sure cure for all the sorrows of the world, and doubted that such a panacea existed.Damn! | Henry Louis Mencken
Soon after this failure, I heard of a new remedy—a sure cure.The Funny Side of Physic | A. D. Crabtre
If she went to bed now she would be sure to suffer all night, and in one of the flasks was a sure cure.John Dough and the Cherub | L. Frank Baum
Having often had recourse to this method, in preserving pencil and crayon drawings, I will warrant it a sure cure.Burroughs' Encyclopaedia of Astounding Facts and Useful Information, 1889 | Barkham Burroughs