a rare fatal hereditary disease, occurring chiefly in infants and children, especially of eastern European Jewish origin, characterized by a red spot on the retina, gradual blindness, and paralysis.
Origin of Tay-Sachs disease
1920–25; named after W. Tay (1843–1927), English physician, and B. Sachs (1858–1944), American neurologist
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019
an inherited disorder, caused by a faulty recessive gene, in which lipids accumulate in the brain, leading to mental retardation and blindness. It occurs mostly in Ashkenazi Jews
Word Origin for Tay-Sachs disease
C20: named after W. Tay (1843–1927), British physician, and B. Sachs (1858–1944), US neurologist
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
A liposomal storage disease that is the infantile type of cerebral sphingolipidosis.GM2 gangliosidosis
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
A genetic disease in which the products of fat metabolism accumulate in the nervous system, causing retardation, paralysis, and death by preschool age. Individuals of eastern European Jewish descent have a higher risk of inheriting Tay-Sachs disease. The disease is named after its describers, British ophthalmologist Warren Tay (1843-1927) and American neurologist Bernard Sachs (1858-1944).
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.