tissue plasminogen activator


noun Biochemistry.

an anticlotting enzyme, naturally occurring in small amounts in the blood.
Pharmacology. the same enzyme, produced in large amounts by genetic engineering techniques for use in dissolving blood clots. Abbreviation: TPA

Nearby words

  1. tissot, james joseph jacques,
  2. tissue,
  3. tissue culture,
  4. tissue lymph,
  5. tissue paper,
  6. tissue respiration,
  7. tissue tension,
  8. tissue type,
  9. tissue typing,
  10. tissue-specific antigen

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019


Medicine definitions for tissue plasminogen activator

tissue plasminogen activator

n.

An enzyme that catalyzes the conversion of plasminogen to plasmin, used to dissolve blood clots rapidly and selectively, especially in the treatment of heart attacks.
A preparation of this enzyme that is produced by genetic engineering and used to dissolve clots blocking coronary arteries in heart attack and cranial arteries in certain cases of stroke.

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Science definitions for tissue plasminogen activator

tissue plasminogen activator

An enzyme that dissolves blood clots. It can be produced naturally by cells in the walls of blood vessels, or prepared through the use of genetic engineering. Tissue plasminogen activator is used in the coronary arteries during heart attacks and in the cranial arteries in certain types of strokes.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.