unipotent

[yoo-nip-uh-tuhnt]

adjective

Biology.

1. (of cells) capable of developing into only one type of cell or tissue.

Word History and Origins

Origin of unipotent¹

uni- + potent ¹

Example Sentences

Identification of unipotent megakaryocyte progenitors in human hematopoiesis.

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In the human model, blood differentiation initiates at the level of multipotent stem cells and passes through a series of increasingly lineage-restricted oligopotent and, finally, unipotent progenitor intermediates.

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Oligopotent progenitors were only a negligible component of the human blood hierarchy in BM, leading to the inference that multipotent cells differentiate into unipotent cells directly by adulthood.

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In a classical view of hematopoiesis, the various blood cell lineages arise via a hierarchical scheme starting with multipotent stem cells that become increasingly restricted in their differentiation potential through oligopotent and then unipotent progenitors.

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Instead, only two progenitor classes predominate, multipotent and unipotent, with Er-Mk lineages emerging from multipotent cells.

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