toward or in the higher part of a stream; against the current.
directed upstream; situated upstream: an upstream journey; an upstream hideout.
Commerce. of or relating to the early stages in the operations of a business or industry, as exploration and production in the oil business (opposed to downstream).
against or opposite to the direction of transcription, translation, or synthesis of a DNA, RNA, or protein molecule.
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2024
How to use upstream in a sentence
While some teams have successfully incorporated Indigenous people into conversations about inclusion and representation, others continue to swim upstream in a constant search for endorsement.Hundreds Of Schools Are Still Using Native Americans As Team Mascots | Hope Allchin | October 12, 2020 | FiveThirtyEight
Automation threatens 50% of upstream energy jobs in the province, according to an August report by EY.After the boom: Canada’s oil capital faces an uncertain future | kdunn6 | September 21, 2020 | Fortune
Providing more integrated campaigns that tie in different capabilities moves publishers further upstream, closer to the decision making, rather than working ad hoc on campaigns.‘Permission to think long term’: The Atlantic digs for deeper, smarter client partnerships | Lucinda Southern | September 18, 2020 | Digiday
Dopamine, for example, only grabs onto the downstream neurons for a bit before it returns back to its upstream neuron—that is, recycled or destroyed.Scientists Used Dopamine to Seamlessly Merge Artificial and Biological Neurons | Shelly Fan | June 23, 2020 | Singularity Hub
Rather, synapses between two neurons change how often they’ll talk to each other—if an upstream neuron reliably passes on information to its downstream partner, then the two are “connected.”Amazingly Detailed Map Reveals How the Brain Changes With Aging | Shelly Fan | June 16, 2020 | Singularity Hub
You wanted to be upstream with the artists, not downstream with the consumers.
The young men and women who went there drank like upstream salmon and studied in between switching kegs at kegger parties.
You don't pay them, they usually make a gift to the cause so it's like the river is running upstream on this one.
And his air of having the inside line has clearly won over admirers upstream as well as down.
Melissa Lion is the author of two novels, Swollen and upstream, both published by Random House.
Tom cast off and Ruth pushed the boat's nose upstream, then settled herself to one of the oars while Uncle Jabez took the other.Ruth Fielding At College | Alice B. Emerson
So he kept on, posting the last of the mermen in his mental relay well away from the city, but swimming upstream himself.Star Born | Andre Norton
After fifteen minutes Hal directed that the skipper take his boat far enough upstream to make up for the drift.
There's a craft moving out from the American shore, about a mile upstream, isn't there!
It was evident that those aboard the craft upstream had made out the pursuing motor boat.
British Dictionary definitions for upstream
in or towards the higher part of a stream; against the current
(in the oil industry) of or for any of the stages prior to oil production, such as exploration or research: Compare downstream (def. 2)
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012