- toward or in the higher part of a stream; against the current.
- directed upstream; situated upstream: an upstream journey; an upstream hideout.
- Commerce. of or relating to the early stages in the operations of a business or industry, as exploration and production in the oil business (opposed to downstream).
- against or opposite to the direction of transcription, translation, or synthesis of a DNA, RNA, or protein molecule.
Origin of upstream
Related Words for upstreamtroublesome, crucial, tough, problematic, arduous, onerous, demanding, severe, strenuous, ambitious, burdensome, laborious, painful, challenging, gargantuan, Herculean, bothersome, exacting, formidable, galling
Examples from the Web for upstream
Contemporary Examples of upstream
You wanted to be upstream with the artists, not downstream with the consumers.Apple Wants Beats So It Can Control You
May 12, 2014
The young men and women who went there drank like upstream salmon and studied in between switching kegs at kegger parties.Joe Paterno Must Retire
September 8, 2011
Melissa Lion is the author of two novels, Swollen and Upstream, both published by Random House.The Stripper Who Lost a Breast
August 21, 2009
The Surge has stemmed the blood loss from the land between two rivers, but upstream from Mesopotamia, the patient still bleeds.How America Blew It in Syria
October 28, 2008
Historical Examples of upstream
If any craft passes you, follow it upstream until you find me.Poisoned Air
Sterner St. Paul Meek
Upstream is right—and I must say the setting pole saved the day.
Rob was swimming on the upstream side, one hand on the stern.
Upstream he caught the dim outline of some dull gray masses.The Red Lure
Roy J. Snell
Two are within a quarter of a mile, one upstream and one downstream.The Topanga Culture Final Report on Excavations, 1948
A. E. Treganza
- in or towards the higher part of a stream; against the current
- (in the oil industry) of or for any of the stages prior to oil production, such as exploration or researchCompare downstream (def. 2)