a variant of the cowpox virus that became established in vaccines derived from cowpox-inoculated humans.
Pathology. an acute infection caused by inoculation with vaccinia virus as a prophylactic against smallpox, characterized by localized pustular eruptions.

Origin of vaccinia

From New Latin, dating back to 1800–10; see origin at vaccine, -ia
Related formsvac·cin·i·al, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Examples from the Web for vaccinia

Contemporary Examples of vaccinia

  • For example, vaccinia immune globulin, or VIG, is stored and ready for the next person who becomes ill from smallpox vaccine.

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Historical Examples of vaccinia

British Dictionary definitions for vaccinia



a technical name for cowpox
Derived Formsvaccinial, adjective

Word Origin for vaccinia

C19: New Latin, from Latin vaccīnus of cows
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for vaccinia




An infection induced in humans by inoculation with the vaccinia virus in order to confer resistance to smallpox; it is usually limited to the site of inoculation.primary reaction
Related formsvac•cini•al adj.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.