[vak-seen or, esp. British, vak-seen, -sin]
- any preparation used as a preventive inoculation to confer immunity against a specific disease, usually employing an innocuous form of the disease agent, as killed or weakened bacteria or viruses, to stimulate antibody production.
- the virus of cowpox, used in vaccination, obtained from pox vesicles of a cow or person.
- a software program that helps to protect against computer viruses, as by detecting them and warning the user.
Origin of vaccine
< New Latin (variolae) vaccīnae cowpox (in title of E. Jenner's treatise of 1798), equivalent to vacc(a) cow + -īnae, feminine plural of -īnus -ine1
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
Examples from the Web for vaccine
The vaccine is delivered through a “carrier virus” that causes a common cold in chimpanzees but does not affect humans.
With Ebola still raging in West Africa, the race to find a vaccine is heating up.
The need for an Ebola vaccine in West Africa has never been greater.
On average, the vaccine has an efficacy of about 60 percent.
With enough changing of the influenza RNA over time, the vaccine no longer provokes the “right” immune response.
A Frankfort man has written a farce comedy called "Vaccine."The New Pun Book
Thomas A. Brown and Thomas Joseph Carey
This latter is the cow-pox, from which Jenner derived the vaccine matter.Cattle and Their Diseases
Phillip, you had the worst cold of your life when you took the vaccine.
One laboratory promised the vaccine in ten days; another said a week.
The public response to the vaccine was little less than monumental.
- a suspension of dead, attenuated, or otherwise modified microorganisms (viruses, bacteria, or rickettsiae) for inoculation to produce immunity to a disease by stimulating the production of antibodies
- (originally) a preparation of the virus of cowpox taken from infected cows and inoculated in humans to produce immunity to smallpox
- (modifier) of or relating to vaccination or vaccinia
- computing a piece of software designed to detect and remove computer viruses from a system
C18: from New Latin variolae vaccīnae cowpox, title of medical treatise (1798) by Edward Jenner, from Latin vacca a cow
Word Origin and History for vaccine
"matter used in vaccination," 1846, from Latin vaccina, fem. of vaccinus "pertaining to a cow" (see vaccination).
Online Etymology Dictionary, © 2010 Douglas Harper
- A preparation of a weakened or killed pathogen, such as a bacterium or virus, or of a portion of the pathogen's structure that upon administration stimulates antibody production against the pathogen but is incapable of causing severe infection.
- A vaccine prepared from the cowpox virus and inoculated against smallpox.
- A preparation of a weakened or killed pathogen, such as a bacterium or virus, or of a portion of the pathogen's structure, that stimulates immune cells to recognize and attack it, especially through antibody production. Most vaccines are given orally or by intramuscular or subcutaneous injection. See Note at Jenner.
A Closer Look: In the 1950s, polio epidemics left thousands of children with permanent physical disabilities. Today, infants are given a vaccine to prevent infection with the polio virus. That vaccine, like most others, works by stimulating the body's immune system to produce antibodies that destroy pathogens. Scientists usually prepare vaccines by taking a sample of the pathogen and destroying or weakening it with heat or chemicals. The inactivated or attenuated pathogen loses its ability to cause serious illness but is still able to stimulate antibody production, thereby conferring immunity. The Salk polio vaccine contains killed virus, while the Sabin polio vaccine contains weakened live poliovirus. (Many scientists no longer consider viruses to be living organisms) Scientists are also able to change the structure of viruses and bacteria at the molecular level, altering DNA so that the potential of the vaccine to cause disease is decreased. New vaccines containing harmless bits of DNA have also been developed.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
The New Dictionary of Cultural Literacy, Third Edition Copyright © 2005 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.