immune system
Americannoun
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The body system in humans and other animals that protects the organism by distinguishing foreign tissue and neutralizing potentially pathogenic organisms or substances. The immune system includes organs such as the skin and mucous membranes, which provide an external barrier to infection, cells involved in the immune response, such as lymphocytes, and cell products such as lymphokines.
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See also autoimmune disease immune response
Other Word Forms
Noun Inflected Forms
Etymology
Origin of immune system
First recorded in 1960–65
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
This allowed them to look for the "similarities and the differences in the important parts of the virus that the immune system responds to", recognising not just one variant but all of them.
From Barron's • Jun. 25, 2026
Others develop autoimmune gastritis, in which the immune system damages stomach cells involved in producing acid and intrinsic factor, the protein needed for vitamin B12 absorption.
From Science Daily • Jun. 25, 2026
The immune system responds, and the next time you eat red meat and related products it identifies those as a threat, resulting in an allergic reaction.
From The Wall Street Journal • Jun. 25, 2026
The young man described a kind of withdrawal: “My immune system broke down. I lost a lot of lean body mass.”
From Salon • Jun. 22, 2026
However, if the bacilli become active—when someone’s immune system is compromised, as with AIDS—they multiply rapidly into a bone-eating, lung-consuming illness that, unless treated, is fatal.
From "Mountains Beyond Mountains" by Tracy Kidder and Michael French
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.