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venlafaxine

American  
[ven-luh-fak-seen, -sin] / ˌvɛn ləˈfæk sin, -sɪn /

noun

Pharmacology.
  1. an oral antidepressant, C 17 H 27 NO 2 , that is thought to inhibit neuronal reabsorption of serotonin, norepinephrine, and possibly dopamine.


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Dr Toby Pillinger says: John should avoid drugs such as venlafaxine, amitriptyline or nortriptyline which raise blood pressure, and would be better suited to citalopram, escitalopram and paroxetine.

From BBC • Oct. 21, 2025

Dr Toby Pillinger says: Sarah should have an antidepressant that avoids weight gain, such as agomelatine, sertraline or venlafaxine rather than amitriptyline or mirtazapine which are more likely to increase weight.

From BBC • Oct. 21, 2025

Researchers also found an increased risk of having a ruptured brain aneurysm for people taking four drugs: the blood thinner warfarin; the antidepressant venlafaxine; the antipsychotic and antiemetic drug prochlorperazine; and the painkiller co-codamol.

From Science Daily • Jun. 5, 2024

The oral antidepressants analyzed were amitriptyline, bupropion, citalopram, desvenlafaxine, doxepin, duloxetine, escitalopram, fluoxetine, mirtazapine, nortriptyline, paroxetine, sertraline, trazodone, and venlafaxine.

From Science Daily • May 30, 2024

The first three “might be considered first choice” by doctors, they write, although the two most effective drugs – amitriptyline and venlafaxine – might still be first choice for severe depression.

From The Guardian • Feb. 21, 2018