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virulent

American  
[vir-yuh-luhnt, vir-uh-] / ˈvɪr jə lənt, ˈvɪr ə- /

adjective

  1. actively poisonous; intensely noxious.

    a virulent insect bite.

    Synonyms:
    venomous
    Antonyms:
    harmless
  2. Medicine/Medical. highly infective; malignant or deadly.

  3. Bacteriology. causing clinical symptoms.

  4. violently or spitefully hostile.

  5. intensely bitter, spiteful, or malicious.

    a virulent attack.

    Synonyms:
    acerbic, vicious

virulent British  
/ ˈvɪrʊlənt /

adjective

    1. (of a microorganism) extremely infective

    2. (of a disease) having a rapid course and violent effect

  1. extremely poisonous, injurious, etc

  2. extremely bitter, hostile, etc

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of virulent

1350–1400; Middle English verulent < Latin vīrulentus, equivalent to vīr ( us ) poison ( see virus) + -ulentus -ulent

Explanation

A virulent disease is one that's infectious, spreading, and making lots of people sick, while a virulent rant is just a verbal attack, causing sickness of the emotional kind. Either way, something virulent puts a strain on the people who get it. Two meanings come out of the roots for virulent: "poisonous" and "spiteful." The virus-carrying meaning of virulent often gets combined with strain, such as in a "virulent strain of the flu." Those who aren’t carrying disease but are still considered virulent most likely lash out at others with a biting tone. Unleashing acid-tongued words on someone would be considered a virulent attack.

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Vocabulary lists containing virulent

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Law showed that the only plausible explanation of repeated outbreaks in crowded stables was a “specific virulent element” passed from one horse to another.

From The Wall Street Journal ● Sep. 7, 2026

But his decision to endorse a major offshore oil exploration project off the coast of the Amazon has garnered virulent criticism from activists.

From Barron's ● Jul. 21, 2026

The traditional method of creating flu vaccines involves growing the virus in eggs - but this can be a problem when there are virulent avian flu strains which can kill the eggs used during manufacturing.

From BBC ● Apr. 21, 2026

We must confront the causal factors of antisemitism honestly and address antisemitism where it is most common and most virulent.

From Los Angeles Times ● Mar. 24, 2026

In 1797 Rush’s opponents were joined by a new and highly virulent voice—that of journalist William Cobbett.

From "An American Plague: The True and Terrifying Story of the Yellow Fever Epidemic of 1793" by Jim Murphy

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