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well-controlled

British  

adjective

  1. regulated, operated, or restrained successfully or strictly

    well-controlled research work

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In February, the FDA Commissioner unveiled a new default position that just one “adequate and well-controlled” study combined with confirmatory evidence will underpin marketing authorization of novel products.

From The Wall Street Journal

"The cartilage structure we have developed is based on stable, well-controlled and reproducible cell lines, and can stimulate bone formation without triggering strong immune reactions. We show that it is possible to create a ready-made, so-called 'off-the-shelf' graft that interacts with the immune system and can repair large bone defects. Because the material can be produced in advance and stored, we see this as an important step toward future clinical use of human bone tissue transplants," says Paul Bourgine, who led the study.

From Science Daily

The agency demanded evidence from an “adequate and well-controlled trial” to prove that reducing the protein in patients’ bloods improves patient outcomes.

From The Wall Street Journal

We recently announced in the New England Journal of Medicine that we are changing the requirement for drug studies from two clinical trials to one well-controlled, well-designed trial.

From The Wall Street Journal

He said Moderna’s late-stage trial wasn’t “adequate and well-controlled” because the control arm did not reflect the “best-available standard of care,” which he deemed a high-dose flu vaccine.

From The Wall Street Journal