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  • Y chromosome
    Y chromosome
    noun
    a sex chromosome of humans and most mammals that is present only in males and is paired with an X chromosome.
  • Y-chromosome
    Y-chromosome
    noun
    the sex chromosome that occurs as one of a pair with the X-chromosome in the diploid cells of the males of many animals, including humans Compare X-chromosome
Synonyms

Y chromosome

American  

noun

Genetics.
  1. a sex chromosome of humans and most mammals that is present only in males and is paired with an X chromosome.


Y-chromosome British  

noun

  1. the sex chromosome that occurs as one of a pair with the X-chromosome in the diploid cells of the males of many animals, including humans Compare X-chromosome

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Y-chromosome Scientific  
  1. The sex chromosome that is paired with an X-chromosome in males. Most of the genes on the X-chromosome determine physical attributes associated with males, such as the development of testes.

  2. See more at sex chromosome See Note at sex


Etymology

Origin of Y chromosome

First recorded in 1920–25

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

"Based on the results, we can proceed with analysis of Y chromosome fragments for comparison with current descendants."

From Science Daily May 4, 2026

"While the direct evidence of physical advantage in transgender people is pretty strong, the evidence of advantage for those with DSD, even though they have a Y chromosome, is highly disputed."

From BBC Mar. 31, 2026

The Y chromosome is especially vulnerable during cell division.

From Science Daily Mar. 20, 2026

Advances in genetic detection have revealed that Y chromosome loss is widespread in older men.

From Science Daily Mar. 20, 2026

The female-producing sperms will each contain a white X and the male-producing sperms will each contain an indifferent Y chromosome.

From A Critique of the Theory of Evolution by Morgan, Thomas Hunt

We then compared the Y-chromosome and mitochondrial DNA, which track the male and female lines of descent, respectively.

From Science Daily May 30, 2026

What Dr Mazanec was looking for was a match with the DNA from the Y-chromosome, which is passed through the male line, from son to son.

From BBC Oct. 28, 2023

The swap didn’t banish the Y chromosome from the recipients, but it culled the chromosome from 49% to 81% of white blood cells—about the same percentage as in many humans with Y-chromosome loss.

From Science Magazine Jul. 13, 2022

Moore had been a keen hobbyist in traditional genealogy and in early consumer genomics, which had allowed the tracking of direct male lines through the Y-chromosome and of maternally inherited mitochondrial DNA.

From New York Times Dec. 27, 2021

"The only thing that puzzles me," Kennon went on, "is how you managed to eliminate the Y-chromosome carriers within the sperm."

From The Lani People by Bone, Jesse F. (Jesse Franklin)

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