hyoscyamine crystallizes in the acicular form, with greater difficulty even than atropine, it also forms less compact crystals.
hyoscyamine gives no crystalline sublimate; it melts at 89°, and appears to volatilise in great part without decomposition.
In 1832 Robiquet discovered codeine; and in 1833 atropine, aconitine, and hyoscyamine were distinguished by Geiger and Hesse.
According to a research by Ladenburg, hyoscyamine is associated with atropine, both in the Belladonna and Datura plants.
hyoscyamine is mainly identified by its power of dilating the pupil of the eye.
The latter plant was considered to contain a new alkaloid, “Duboisine,” but duboisine is a mixture of hyoscyamine and hyoscine.
I think, therefore, that both Planta and Schmidt must have worked with a mixture of atropine and hyoscyamine.
hyoscyamine neutralises acids fully, and forms crystallisable salts, which assume for the most part the form of needles.
The derivative preparations, hyoscyamine and hyoscyamia, are preferable for use in this class of cases.
hyoscyamine hy·o·scy·a·mine (hī'ə-sī'ə-mēn')
A poisonous white crystalline alkaloid isometric with atropine and having similar uses but more potent effects.