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antagonize

American  
[an-tag-uh-nahyz] / ænˈtæg əˌnaɪz /
especially British, antagonise

verb (used with object)

  • antagonizes,
    present (3rd person singular)
  • antagonized,
    past participle,  past
  • antagonizing
    present participle
  1. to make hostile or unfriendly; make an enemy or antagonist of.

    His speech antagonized many voters.

  2. to act in opposition to; oppose.


verb (used without object)

  • antagonizes,
    present (3rd person singular)
  • antagonized,
    past participle,  past
  • antagonizing
    present participle
  1. Rare. to act antagonistically.

antagonize British  
/ ænˈtæɡəˌnaɪz /

verb

  1. to make hostile; annoy or irritate

  2. to act in opposition to or counteract

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Etymology

Origin of antagonize

First recorded in 1625–35, antagonize is from the Greek word antagōnízesthai to contend against, dispute with. See ant-, agonize

Explanation

To antagonize is to provoke someone to react angrily. If your mother tells you to stop antagonizing your brother, she's asking you to stop making him mad. Antagonize shares the same Greek roots with the word agony, so think about how much agony you cause your siblings when you tease and goad them into getting angry. Bugs Bunny is known to antagonize Elmer Fudd, who hunts but never does catch that wabbit. Actually Bugs antagonizes every cartoon character he comes into contact with! In English class, you'll often be asked to name the antagonist of a story or novel, the character who provokes the main character to act.

Keep Reading on Vocabulary.com

Vocabulary lists containing antagonize

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The plan could result in putting more U.S. troops closer to the Russian border, an outcome likely to antagonize Moscow.

From The Wall Street Journal Apr. 8, 2026

“Halfrican” explores the theme of “in between-ness” and encourages viewers to antagonize preconceived notions of identity.

From Los Angeles Times Dec. 3, 2024

There is more willingness to embrace the youth vote, rather than antagonize it, as far as campaign strategy goes.

From Slate Aug. 19, 2024

“When we are fighting for our survival, we can’t afford to antagonize either Biden or Trump,” Mr. Merezhko said.

From New York Times Apr. 19, 2024

I'll just have to be careful not to antagonize anyone.

From "Invisible Man" by Ralph Ellison

However, naltrexone, in both short- and long-acting forms, has the opposite pharmacology: it antagonizes mu receptors, occupying them without activating them.

From Scientific American Sep. 13, 2023

It all makes for a slight but satisfying Gru origin story, as the budding baddie tries to impress the Vicious 6 and antagonizes Arkin’s vengeful Wild Knuckles along the way.

From Washington Post Jun. 28, 2022

The border with Pakistan is sometimes closed and sometimes open, a fitful pattern that antagonizes the Afghan pomegranate farmers and buyers to no end as they try to time their harvests, sales and exports.

From New York Times Nov. 21, 2021

It doesn’t stop the smoldering resentment that I feel deep down when she antagonizes me.

From Slate Aug. 30, 2019

Nothing worries and antagonizes a female bear more than to have people between her and her brood.

From "A Walk in the Woods" by Bill Bryson

But Adeyemi describes suffering somatic pain and panic attacks, alleging she is still being antagonized behind the scenes.

From Salon Jul. 31, 2026

Some also contend the deal has unnecessarily antagonized China, Australia’s main trading partner.

From The Wall Street Journal Oct. 21, 2025

So, people who are sophisticated litigators often don’t do that because it so often fails, and all you’re left with is an angered and antagonized judge who you’ve just called biased.

From Slate Apr. 11, 2024

Instead, he says, the experiment merely shows that, when antagonized the snakes are likely to put up a more spirited defense.

From Science Magazine Apr. 3, 2024

He was deeply antagonized by these men, but he knew they were simply carrying out a job assigned to them.

From "Across Five Aprils" by Irene Hunt

And, two, how did the Ottawa captain feel about the White House posting an A.I.-generated video on its TikTok account that purported to show Tkachuk antagonizing the country where he works?

From Slate Feb. 27, 2026

She needs to maintain her popular tough stance on China without overly antagonizing Japan’s No. 2 customer for exports.

From Barron's Feb. 10, 2026

Zohran Mamdani, who just swept to victory in the New York City mayoral race, already faces his next big challenge: making the right hires without alienating loyalists or further antagonizing skeptics.

From The Wall Street Journal Nov. 8, 2025

On the other, you have Baier trying to show he's tough by antagonizing and talking over her.

From Salon Nov. 4, 2024

Terryl felt like her mother blamed her for antagonizing Danny, and making things worse.

From "A Deadly Wandering: A Mystery, a Landmark Investigation, and the Astonishing Science of Attention in the Digital Age" by Matt Richtel

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