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Showing results for painkiller. Search instead for Buying painkillers.
Synonyms

painkiller

American  
[peyn-kil-er] / ˈpeɪnˌkɪl ər /

noun

painkillers plural
  1. a drug, treatment, or anything else that relieves pain, especially an analgesic.


painkiller British  
/ ˈpeɪnˌkɪlə /

noun

  1. an analgesic drug or agent

  2. anything that relieves pain

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Inflected Forms

Nouns

Etymology

Origin of painkiller

An Americanism dating back to 1850–55; pain + killer

Explanation

A painkiller is a medicine that's used to dull or relieve pain, like the painkiller your dad gives you when you have a bad headache. Painkillers are meant to do exactly what their name says: to kill pain. You can also call this kind of medication an analgesic. These range from aspirin and acetaminophen, which are sold over the counter to treat minor aches and pains, to powerful anesthetics administered by doctors before surgery. If you get your wisdom teeth removed, you'll most likely need a painkiller during and after the procedure.

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Scientific research has not identified causality between taking the painkiller and the development of those conditions in children.

From Barron's Jul. 13, 2026

The painkiller is usually prescribed for relatively minor conditions, such as aching joints or people recovering from surgery.

From The Wall Street Journal Jul. 12, 2026

While still an effective painkiller, ibuprofen can be a better choice for period pain because it blocks the production of prostaglandins - the chemical responsible for causing the cramping contractions of muscles in the womb.

From BBC Jun. 14, 2026

He previously wrote about Samsung from Seoul, but in prior stints at the Journal's New York, Atlanta and Chicago offices, he covered Wall Street's biggest buyers, painkiller addiction, airlines and food.

From The Wall Street Journal Jan. 31, 2026

"A monochrome Jackson Pollock," Jane says, and then tells Tiny, "We gotta bolt. This band is like a root canal sans painkiller."

From "Will Grayson, Will Grayson" by John Green and David Levithan

Lilly is expanding into non-opioid painkillers, a neuroscience growth area, despite a history of shelved candidates.

From Barron's Jun. 16, 2026

Kevin Liu, an oil and gas analyst with Bloomberg Intelligence, compared the SPR releases as a painkillers for the oil market.

From MarketWatch May 28, 2026

In India, 40 million vultures were reduced to nearly zero by the presence of veterinary painkillers, lethal to vultures, in cattle carcasses.

From The Wall Street Journal May 1, 2026

"They admitted him to hospital where he developed a bad fever, really bad diarrhoea. He was on a drip, he needed constant fluids, constant painkillers," said Gareth.

From BBC Mar. 24, 2026

“You woke up once, but you fell back asleep. Dr. Han said the painkillers would knock you out, so I guess they did the job.”

From "Internment" by Samira Ahmed

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