[ as-per-in, -prin ]
/ ˈæs pər ɪn, -prɪn /
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noun, plural as·pi·rin, as·pi·rins.
Pharmacology. a white, crystalline substance, C9H8O4, derivative of salicylic acid, used as an anti-inflammatory agent and to relieve the pain of headache, rheumatism, gout, neuralgia, etc.; acetylsalicylic acid.
an aspirin tablet: I took two aspirin and went right to bed.
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Origin of aspirin

First recorded in 1899; originally a German trademark, equivalent to A(cetyl) + Spir(säure) “salicylic acid” + -in noun suffix; see acetyl, spirea, -in2


aspirant, aspirate, aspirin
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use aspirin in a sentence

British Dictionary definitions for aspirin

/ (ˈæsprɪn) /

noun plural -rin or -rins
a white crystalline compound widely used in the form of tablets to relieve pain and fever, to reduce inflammation, and to prevent strokes. Formula: CH 3 COOC 6 H 4 COOHChemical name: acetylsalicylic acid
a tablet of aspirin

Word Origin for aspirin

C19: from German, from A (cetyl) + Spir (säure) spiraeic acid (modern salicylic acid) + -in; see also spiraea
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Scientific definitions for aspirin

[ ăspər-ĭn, ăsprĭn ]

A white crystalline compound derived from salicylic acid and used in medicine to relieve fever and pain and as an anticoagulant. Also called acetylsalicylic acid. Chemical formula: C9H8O4.

A Closer Look

Ninety percent of the population experiences at least one headache each year. The most common type is a tension headache, which is caused by stress and is characterized by tightening of the muscles in the base of the neck and along the scalp. Aspirin alleviates headaches by blocking the body's production of prostaglandins, hormones that contribute to pain by stimulating muscle contraction and blood vessel dilation. For thousands of years, people chewed the bark of willow trees to control headache and other pain. The study of the properties of this medicinal plant led German chemist Hermann Kolbe to synthesize acetylsalicylic acid (ASA), a building block of aspirin, in 1859. A pure form of ASA wasn't prepared until 1897, by Felix Hoffman, a chemist in the Bayer chemical factory in Germany. After publication of successful clinical trials, aspirin was distributed in powder form in 1899 and as a tablet in 1900. Aspirin possesses a number of properties that make it one of the most recommended drugs. Besides being an analgesic, or pain reliever, it also reduces inflammation that often accompanies injuries or diseases, such as arthritis. It is also an antipyretic compound, or fever reducer. Aspirin is the only over-the-counter analgesic approved for prevention of cardiovascular disease. New research suggests that aspirin may also decrease the risk of some forms of stroke. Additional studies indicate that aspirin may play a role in reducing the risks of ovarian cancer.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.